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Lip Metastasis: An Overview of the Last 30 Years

Metastasis to the oral cavity is a rare event and constitutes 1% of all oral cavity malignancies. 412 oral soft tissue metastasis were documented in scientific literature, in a period between 1937 and 2015; gum was the site most involved. We had found only 8 cases of oral metastasis on the lips searching on PubMed with the keywords “oral mestastasis in lips”, “lip metastasis”. The primary malignant tumor that most frequently metastases at the labial level is certainly the renal tumor with 5 cases out of 8. In 5 cases the upper lip was affected, there was 1 case in which metastasis was present in both lips, and this is a very interesting data because the other malignant disease are more frequent in the lower lip.


Cinzia Casu, Luca Viganò and Matteo Fanuli

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